Roskamp laboratories
Cell and Molecular Biology Laboratory
University of South Florida,
Tampa,
Florida,
U.S.A.
The Roskamp Institute is a state approved basic science research facility operating
in conjunction with a fully active memory disorder clinic (MDC). The laboratories of
the Roskamp Institute encompass a broad range of scientific approaches to
understanding the cause of and potential therapies for Alzheimer's disease; however
most of the work is at the cell and molecular biology level. Researchers in the
Roskamp Institute were among those who identified mutations in the ß-amyloid
precursor protein gene which cause early onset Alzheimer's disease. Since then, the
key role of the ß-amyloid peptide in AD pathogenesis has largely been accepted, and
much of the research in the Roskamp Institute involves experimentation on the
physiologic properties of this peptide in various laboratory systems. In particular
the effects and mechanism of action of ß-amyloid on the cerebrovasculature are
being pursued. Twenty-seven scientists currently work in the Institute which is
funded by Robert and Diane Roskamp, NIH, the Veteran's Administration and the
National Alzheimer's Association. The Institute is housed in the Department of
Psychiatry and Behavioral Medicine at the USF campus but also includes affiliated
laboratories at the James A. Haley Veterans Administration Hospital. The
juxtaposition of clinical and research components facilitates the efforts of the
Institute, which are to identify compounds likely to be efficacious in the treatment of
Alzheimer's disease.
WWW Link ---->
The Roskamp Institute for Research into Neurodegenerative Diseases
E-Mail ---->
Roskamp@hsc.usf.edu
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